Search on: P21-ACTIVATED KINASES 
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Descriptor English:   p21-Activated Kinases 
Descriptor Spanish:   Quinasas p21 Activadas 
Descriptor Portuguese:   Quinases Ativadas por p21 
Tree Number:   D08.811.913.696.620.682.700.596
D12.644.360.552
D12.776.476.548
Definition English:   A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEINS. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization. 
History Note English:   2008 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   52745 
Unique Identifier:   D054462 

Occurrence in VHL: 		 

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